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A Comprehensive Review of Idiopathic Pulmonary Arterial Hypertension: Epidemiology, Pathogenesis and Management.

Marcus Beaver

Idiopathic Pulmonary Arterial Hypertension (IPAH) is a rare and life-threatening disease that affects the pulmonary vasculature. It is characterized by increased pulmonary artery pressure and resistance, leading to right heart failure and death. The exact cause of IPAH is unknown, but it is thought to be a complex interplay between genetic, environmental, and epigenetic factors. The management of IPAH involves a multidisciplinary approach, including pharmacotherapy, oxygen therapy, and supportive care. In this mini-review, we provide a comprehensive overview of the epidemiology, pathogenesis, and management of IPAH.