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Eosinophilic Enteritis Due to Cows Milk Allergy: Possible Cause of Anastomosis Failure?

Satoshi Yokoyama, Akinori Sekioka, Hirofumi Utsunomiya

Reports of cases of Cow's Milk Allergy [CMA] after neonatal gastrointestinal surgery have recently increased. In recent years it has been suggested that the development of CMA after gastrointestinal surgery in newborn infants is due to an immune function. In addition, the development of CMA might be synergistically exacerbated by congenital abnormalities of the intestinal mucosa, general conditional changes and local damage to the intestine by invasive surgery, and poor pre- or post-surgical nutrition. CMA is manifested by a variety of symptoms, which cause problems such as mild vomiting and bloody stool, decreased activity, poor oral intake, and ileus. CMA may also rarely cause gastrointestinal perforation. Here, we report a case of a newborn infant who developed CMA following repair of focal small intestinal perforation, in which eosinophilic enteritis was suspected to be a possible cause of anastomosis leakage.