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Invasive squamous cell cancer arising in a mature cystic teratoma: a case report in a 75-year-old Ghanaian woman.

Der EM, Asomma K2, Ayete L

Mature cystic teratoma (MCT) of the ovary is a common benign adnaexal tumour in females. The most common malignant transformation is squamous cell carcinoma (SCC) and this commonly occurs in young women. We report a case of a 75-year woman, para 9 (5 alive and 4 dead) who presented to the outpatient department (OPD) of the Tamale Teaching Hospital (TTH) with abdominal pains of a year’s duration. Initial physical examination revealed a pelvic mass. An abdomino-pelvic ultrasound diagnosed a right mature cystic teratoma (dermoid cyst) with right cystadenoma as the differential diagnosis. However, an invasive SCC arising in a MCT was made after histopathological examination of the surgical sample. The current case report illustrates the difficulties in preoperative diagnosis of invasive SCC in MCT. Adequate sampling followed by histopathological examination has important role in the diagnosis of SCC arising in MCT.