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Ovarian function preservation of low grade endometrial stromal sarcoma at stage II: A case report and review of literature.

Yinjuan Chang, Juanqing Li, Yongshen Fan, Yibing Lan, Haiyan Shi, Jianhong Zhou

Endometrial stromal sarcoma (ESS) is a rare form of uterine cancer. Low grade endometrial stromal sarcoma (LG-ESS) is a special type of ESS, has an indolent clinical course, and it is associated with a favorable prognosis. It is very challenging to diagnose LG-ESS preoperative. The standard treatment for LG-ESS is surgical, with a total hysterectomy and bilateral salpingo-oophorectomy (BSO). There is no consensus regarding the role of adjuvant treatment, including chemotherapy, radiation, and hormonal treatment. Here we report a case of a 27-yearold female with LG-ESS at stage II who underwent total hysterectomy and salpingectomy. Medroxyprogesterone acetate and tamoxifen were then administered to inhibit tumor recurrence. Ovarian function was preserved for this young patient, with no sign of recurrence at the 11-months follow-up.