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Personalized organ survival strategies based on cellular and molecular information

Elyas K K

Human Leucocyte Antigen (HLA) or human Major Histocompatibility Complex (MHC) molecules are the most polymorphic gene clusters that are involved in immune recognition. Though polymorphic, these genes are inherited as a cluster without much recombination. With the advancement of molecular techniques like high resolution typing of HLA alleles using sequence- specific primer polymerase chain reaction, Flow cytometry, Luminex technology, next generation sequencing, etc.,