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The onset of HLA-B27-associated diseases in diabetic patient during a period of religious fasting.

Zhenyun Lin1, Binbin Zhu2 and Xiuming Jin2*

The association of HLA-B27 with its associated diseases is far from complete. The role of HLA-B27 in disease susceptibility is still not known, although many suggestions have been proposed. We are now presenting a diabetic patient who suffered three different HLA-B27-associated diseases (including acute anterior uveitis, ulcerative colitis and ankylosing spondylitis) in the last three years as a result of prolonged fasting for one week each year.