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Therapeutic activity study in fungal disease by Azadirachta indica

Shubham Sharma, Lovely Chaurasia, Sunayana Tyagi

The aim to present that fungal infection is one of the most common skin problems throughout the world. There are broad choices of treatment from liquid to semi-solid dosage forms. Preparation has more than two or two herbal ingredients called polyherbal preparation. As compared to synthetically produced drugs, phytochemicals are a better source of medicine. Drug originated from herbal origin used in traditional system of medicine such as Unani, Siddha, tribal and Ayurveda medicines since pristine times, Ayurveda is most broadly accepted system of medicine.

For few studies shows antifungal and antimicrobial effect on fungal and microbial growth Azadirachtin that is a tetranortriterpenoid present in seeds of plants. The extract of neem leaves gives antibacterial activity. Due to antioxidant properties, neem plays an important role as free radical scavenging.

This can be extract by following method-infusion, maceration, percolation and decoction which shows best effect in antimalarial activity, antiviral, antifungal, anti-diabetics, anticancer, anti-inflammatory, and antioxidant and immuno modulator and growth etc. There is a need of reduction in the use of chemical substance as anti-fungal agents to fight infections caused by fungal that are resistant to the use of synthetic anti-fungal agent.